Recent autumn FRCR part 1 2013 (2)

Cancer/Radiobiology

1. P53 -?check point
2. RB gene ? E2F factor
3. Integrins - Bind cell to extra cellular matrix
4. Nucleotide excision repair
5. BRCA 1
6. P53 linked enzyme- Mdm2 ubiquitin ligase
7. HIF bind ? ezyme
8. HIF Induces? angiogenesis
9. Stable chromosomal aberration ? Translocation
10. A/b value of confluent skin reaction?
11. BED caluculation for ?
12. Problem on surviving fraction of cells (platting eficiency value given )
13. Vincristine acts on which phase
14. Epigenetics  ?
15. High let radiation ? cell cycle phase
16. 2.5 mv alpha rays ?hav more LET than 100 mv
17. OER related ?  LET radiations
18. No of cells in a clinically visible tumor
19. Cerebrovascular syndrome ? whole body irridiation  
20. Amifostine has ? protective mechanism
21. Lifraumeni Syndrome - Autosomal dominant
22. Allelic imbalence can be detected by ?
23. Myc oncogene functions
24. Hnpcc ? Mismatch repair
25. Apc?
26. Which Is cancer stem cell
27. Hyperfractionation ? Spares Late effects
28. Which Is High LET ? Carbon Ions
29. VHL ? PTEN Mutation